If you like it, go for it. Blogging takes a lot of energy and commitment, so go with a name that resonates with you first and foremost - you want it to be a place you really enjoy writing. That said, it can be helpful to 'brand' something in a way that's easy to remember - easy to spell, easy to pronounce. You can test that by simply asking people to spell it when you say it to them, or by showing them the name and asking them to say it. People may have trouble with "empiric".

Personally I like the name -- both because it accurately describes the subject and motivation for your blog and because of the catchy half-rhyme / assonance created between "-piric" and "spirit".

However, I wonder what percentage of the general population is actually familiar with the words "empiric" and "empirical". You do risk losing a percentage of your audience if the name of your website turns out to be unintelligible to them. And, unfortunately, I'd expect that to be the case.

I'm not suggesting that you avoid words such as "empiric" within your blog articles. For there readers who perhaps aren't acquainted with the word will be aided by the context. However, with a name, there is no context. And a name, if partially forgotten, acts as a deterrent against word-of-mouth growth.

As a branding expert I don't like it for the reason it is too hard to remember, spell and share.

That being said focus on the business and spend little time with the name, many people get 'stuck' with finding the perfect name when they have not tested the viability of their product, service or business.

Hope this helps.

At first blush, when I see the word "Spirit" I think of the airline. Empiric resonates with me if available for a name. A few questions I would ask myself before starting who is the audience, will this monetized, and who are potential advertisers.