Hi. I am a business coach and mentor and have started a number of successful businesses.
There is no reason why you can't have two different businesses in the same location.
There are two questions I would ask:
Will the two businesses work to complement each other?
Are there aspects of either business that will adversely affect the other?
E.g. The smell of nail products/cleaners in the same area as fresh food products.
Could there be questions of hygiene, depending on how the space is separated?
I hope this helps give you food for thought.
Regards
Rick